Journal Search Engine
Search Advanced Search Adode Reader(link)
Download PDF Export Citaion korean bibliography PMC previewer
ISSN : 1738-0294(Print)
ISSN : 2288-8853(Online)
Journal of Mushrooms Vol.12 No.1 pp.1-7
DOI : https://doi.org/10.14480/JM.2014.12.1.1

Antioxidant, anti-acetylcholinesterase and xanthine oxidase inhibitory activities of three extracts from Phellinus igniarius

Tae Soo Lee2*, Ga-Heon Jin, Min Woong Lee1, Kyung Hoan Im2
2Division of Life Sciences, Incheon National University,(Songdo-dong) 119 Academy-ro, Yeonsu-gu, Incheon, Korea
Department of Ophthalmic Optics, Shinheung University 95 Hoam-ro, Uijeongbu, Gyeongggi 480-701, Korea
1Department of Life Sciences, Dongguk University, 30, Pildong-ro, Seoul, 100-175, Korea
Received March 14, 2014 , Revised April 1, 2014 , Accepted April 2, 2014

Abstract

This study was initiated to investigate antioxidant, anti-acetylcholinesterase, and xanthine oxidase inhibitory activitiesand properties of fruiting bodies, mycelia, and fermentation culture filtrates from Phellinus igniarius. The contents of total phenolsand flavonoid of fruit bodies, mycelia, and culture filtrate were 15.35-1.36 mg/g, 10.35-7.85 mg/g, and 8.25-5.36 mg/g. The 1,1-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging abilities of the extracts from the fruiting bodies, mycelia, and culture filtrateswere 90.25-95.60%, 78.82-85.24%, and 76.32-82.50% at 50-400 μg/mL, respectively. The chelating ability of fruiting bodyextract on ferrous ions was higher than those of mycelia and culture filtrates tested. The anti-acetylcholinesterase inhibitoryactivity of the fruiting body extract at 400 μg/mg exhibited 91.10% on AChE, which is lower than that of positive control,galanthamine (94.82%). The xanthine oxidase inhibitory activities of the fruiting bodies, mycelia, and culture extract were85.47%, 78.13%, and 72.49% at 400 μg/mL, respectively. Overall, the fruiting body extract has better anti-acetylcholinesterase,antioxidant and xanthine oxidase inhibitory activities than those from mycelia and culture filtrate.

 

Reference